Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis
www.elsevier.com/locate/jethpharm. Nacionalidad: Kichwa, Awa
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Graz / Journal of Ethnopharmacology
2017
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oai:localhost:28000-43342017-06-30T08:03:55Z Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis Journal of Ethnopharmacology Gachet, Mar?a Salom? Salazar Lecaro, Javier K?iser, Marcel Brun, Reto Navarrete, Hugo Mu?oz, Ricardo A. Bauer, Rudolf Sch?hly, Wolfgang PLANTAS MEDICINALES PR?CTICAS MEDICINALES LEISHMANIASIS DONOVANI CURANDEROS MEDICINA ANCESTRAL MEDICINA TRADICIONAL www.elsevier.com/locate/jethpharm. Nacionalidad: Kichwa, Awa "AIM OF THE STUDY: For the assessment of the in vitro anti-protozoal potential of plants traditionally used in Ecuador in the treatment of leishmaniasis, a combined approach based on interviews with healers as well as a literature search was carried out. MATERIALS AND METHODS: From three regions of Ecuador, 256 local healers called ""Agents of Traditional Medicine"" (ATMs) were interviewed about their knowledge of the use of plants to treat and heal the illness recognized by the ATMs as leishmaniasis. From literature sources, 14 plants were identified as being used in the treatment of leishmaniasis. Subsequently, plant material was collected from a representative selection of 39 species. A total of 140 extracts were screened in vitro against Leishmania donovani, Plasmodium falciparum, Trypanosoma brucei rhodesiense and Trypanosoma cruzi. Additionally, these extracts were evaluated for their anti-microbial activities using five gram-positive and -negative bacteria as well as C?ndida albicans. RESULTS AND CONCLUSIONS: The survey resulted in 431 use-records for 145 plant-taxa used for the treatment of leishmaniasis. The 10 most frequently reported taxa accounted for 37.7% of all records. In the case of leishmaniasis, activity was observed for Elephantopus mollis, Minquartia guianensis, Bocconia integrifolia, Gouania lupuloides, Scoparia dulces, en as-yeta-unidentified species of Piper and Brugmansia. For the leaves of M. guianensis and the twigs and bark of G. lupuloides a good selectivity index (SI) was found. IC(50) values and the SI of active plant extracts are presented." 2017-06-29T17:50:04Z 2017-06-29T17:50:04Z 2010 article Gachet, Mar?a Salom?; Salazar Lecaro, Javier; K?iser, Marcel; Brun, Reto; Navarrete, Hugo; Mu?oz, Ricardo A; Bauer, Rudolf; Sch?hly, Wolfgang. (2010). Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis. Journal of ethnopharmacology. Journal of ethnopharmacology. Institute of Pharmaceutical Science. Graz. Pp. 184-197 28 http://repositorio.educacionsuperior.gob.ec/handle/28000/4334 eng pp. 184-197 Graz / Journal of Ethnopharmacology |
| institution |
SENESCYT |
| collection |
Repositorio SENESCYT |
| biblioteca |
Biblioteca Senescyt |
| language |
eng |
| format |
Artículos |
| topic |
PLANTAS MEDICINALES PR?CTICAS MEDICINALES LEISHMANIASIS DONOVANI CURANDEROS MEDICINA ANCESTRAL MEDICINA TRADICIONAL |
| spellingShingle |
PLANTAS MEDICINALES PR?CTICAS MEDICINALES LEISHMANIASIS DONOVANI CURANDEROS MEDICINA ANCESTRAL MEDICINA TRADICIONAL Gachet, Mar?a Salom? Salazar Lecaro, Javier K?iser, Marcel Brun, Reto Navarrete, Hugo Mu?oz, Ricardo A. Bauer, Rudolf Sch?hly, Wolfgang Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis |
| description |
www.elsevier.com/locate/jethpharm. Nacionalidad: Kichwa, Awa |
| author |
Gachet, Mar?a Salom? Salazar Lecaro, Javier K?iser, Marcel Brun, Reto Navarrete, Hugo Mu?oz, Ricardo A. Bauer, Rudolf Sch?hly, Wolfgang |
| author_facet |
Gachet, Mar?a Salom? Salazar Lecaro, Javier K?iser, Marcel Brun, Reto Navarrete, Hugo Mu?oz, Ricardo A. Bauer, Rudolf Sch?hly, Wolfgang |
| author_sort |
Gachet, Mar?a Salom? |
| title |
Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis |
| title_short |
Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis |
| title_full |
Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis |
| title_fullStr |
Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis |
| title_full_unstemmed |
Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis |
| title_sort |
assessment of anti-protozoal activity of plants traditionally used in ecuador in the treatment of leishmaniasis |
| publisher |
Graz / Journal of Ethnopharmacology |
| publishDate |
2017 |
| url |
http://repositorio.educacionsuperior.gob.ec/handle/28000/4334 |
| _version_ |
1634995240655912960 |
| score |
11,871979 |