Fabrication of 3D bioactive ceramic scaffolds by robocasting

Tricalcium phosphate ceramics are bioactive and osteoconductive biomaterials that support cellular functions and can develop appropriate mechanical characteristics for bone tissue engineering. Fast prototyping techniques permit to obtain accurate control over scaffolding architecture with high repro...

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Autor Principal: Abdal-hay, Abdalla
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Lenguaje:eng
Publicado: 2016
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Acceso en línea:http://repositorio.educacionsuperior.gob.ec/handle/28000/2612
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spelling oai:localhost:28000-26122017-04-11T15:04:33Z Fabrication of 3D bioactive ceramic scaffolds by robocasting Abdal-hay, Abdalla BIOMATERIALS BIOREACTOR BONE TISSUE ENGINEERING FLEXIBLE SCAFFOLDS Tricalcium phosphate ceramics are bioactive and osteoconductive biomaterials that support cellular functions and can develop appropriate mechanical characteristics for bone tissue engineering. Fast prototyping techniques permit to obtain accurate control over scaffolding architecture with high reproducibility. Flexible composites are considered to promote mechano-biological stimulation during cell culture. The aim of this study is to fabricate flexible bioceramic scaffolds by robocasting and to determine biological improvements related to their added flexible properties. Characterized 3D ? - TCP/gelatin scaffolds with interconnected porous structure were fabricated using robocasting. SEM micrographs showed fabricated porous scaffolds with desired pore size (~200 ?m), rods diameter (~840 ?m), porosity and mechanical strength. Alamar Blue assay was performed for static and dynamic cultures along 21 days. Oscillatory flow conditions allowed considerable higher cell proliferation compared with static conditions. Universidad De Cuenca http://link.springer.com/chapter/10.1007%2F978-3-319-13117-7_44 2016-10-28T20:06:44Z 2016-10-28T20:06:44Z 2014 article Andrade, S. et al. (2014). Fabrication of 3D bioactive ceramic scaffolds by robocasting. VI Latin American Congress on Biomedical Engineering CLAIB 2014. Vol 49. pp. 167-169. 978-3-319-13117-7 1680-0737 http://repositorio.educacionsuperior.gob.ec/handle/28000/2612 eng restrictedAccess pp. 167-169.
institution SENESCYT
collection Repositorio SENESCYT
biblioteca Biblioteca Senescyt
language eng
format Artículos
topic BIOMATERIALS
BIOREACTOR
BONE TISSUE ENGINEERING
FLEXIBLE SCAFFOLDS
spellingShingle BIOMATERIALS
BIOREACTOR
BONE TISSUE ENGINEERING
FLEXIBLE SCAFFOLDS
Abdal-hay, Abdalla
Fabrication of 3D bioactive ceramic scaffolds by robocasting
description Tricalcium phosphate ceramics are bioactive and osteoconductive biomaterials that support cellular functions and can develop appropriate mechanical characteristics for bone tissue engineering. Fast prototyping techniques permit to obtain accurate control over scaffolding architecture with high reproducibility. Flexible composites are considered to promote mechano-biological stimulation during cell culture. The aim of this study is to fabricate flexible bioceramic scaffolds by robocasting and to determine biological improvements related to their added flexible properties. Characterized 3D ? - TCP/gelatin scaffolds with interconnected porous structure were fabricated using robocasting. SEM micrographs showed fabricated porous scaffolds with desired pore size (~200 ?m), rods diameter (~840 ?m), porosity and mechanical strength. Alamar Blue assay was performed for static and dynamic cultures along 21 days. Oscillatory flow conditions allowed considerable higher cell proliferation compared with static conditions.
author Abdal-hay, Abdalla
author_facet Abdal-hay, Abdalla
author_sort Abdal-hay, Abdalla
title Fabrication of 3D bioactive ceramic scaffolds by robocasting
title_short Fabrication of 3D bioactive ceramic scaffolds by robocasting
title_full Fabrication of 3D bioactive ceramic scaffolds by robocasting
title_fullStr Fabrication of 3D bioactive ceramic scaffolds by robocasting
title_full_unstemmed Fabrication of 3D bioactive ceramic scaffolds by robocasting
title_sort fabrication of 3d bioactive ceramic scaffolds by robocasting
publishDate 2016
url http://repositorio.educacionsuperior.gob.ec/handle/28000/2612
_version_ 1634995073478295552
score 11,871979